Syngulon Patents & Intellectual Property

Syngulon patents protect key technologies in antibiotic-free microbial selection, bacteriocin production and engineering, fermentation processes and antimicrobial applications. Our intellectual property portfolio includes granted patents in multiple jurisdictions and supports technology licensing across biotechnology, pharmaceutical, animal health and industrial applications.

Syngulon Patents by Technology Area

Patents on Antibiotic-Free Selection Technology

US Patent 9,333,227

On May 10, 2016 the USPTO issued a first patent to Syngulon for the use of bacteriocin/immunity in any bacteria, yeast or algae for “Controlled growth of microorganisms“.

US Patent 10,188,114

On January 29, 2019, USPTO issued a second patent to Syngulon covering the use of bacteriocin/immunity for the “Controlled growth of microorganisms“s.

US Patent 11,427,800

On August 30, 2022, USPTO issued a third patent to Syngulon covering the use of bacteriocin/immunity for the “Controlled growth of microorganisms“.

US Patent 12,297,422

On May 13, 2025, USPTO issued a fourth patent to Syngulon covering the use of bacteriocin/immunity for the “Controlled growth of microorganisms“.

Other patents: CN ZL 201480057387.2/ZL 201910882176.7 + EP3035802B1 + BR112016003533-0/BR1220210154171 + IN389267

US Patent 11,932,672

On March 19, 2024, USPTO issued a first patent “Fermentation Process” to Syngulon and Université libre de Bruxelles (ULB) that specifically claims the use of “immunity only” and the control of the selection circuit in accordance with production fermentation processes.

Other patent: KR 10-2777327

These issued patents covering our antibiotic-free selection technology are available for licensing in all fields of use on a non-exclusive base.

Patents on Bacteriocin Production, Engineering and Applications

US Patent 11,492,651 / US Patent 12,195,780

On November 8, 2022 the USPTO issued a first patent to Syngulon on “Methods and compositions for making bacteriocin and antimicrobial peptides“. The second patent was issued on January 14, 2025.

Other patent: JP 7340517/7724815 + CN ZL 2018 8 0060807.0 + BR 122024008921-1 + IN599293

US Patent 12,173,343

On December 24, 2024 the USPTO issued a first patent to Syngulon on “Engineering Antimicrobial Peptides”.

US Patent 12,234,299

On February 25, 2025 the USPTO issued a patent to Syngulon and Université Catholique de Louvain (UCLouvain) on “Peptides for inducing bacteriocin synthesis and methods to identify and/or select and/or optimize the same“.

Licensing Syngulon’s Patented Technologies

Syngulon’s patented technologies are available for licensing and partnering across selected fields of use.

These patent families support Syngulon’s work in bacteriocin engineering, antibiotic-free selection, contamination control and therapeutic applications.

Supported by the Wallonia Region of Belgium.